Introduction to Large Scale Neural Recording with SiNAPS and OmniPlex HD

Harvey Wiggins

Recent developments in neural interface technologies are leading a path to ever more detailed exploration of neural functions. Miniaturization and increases in electrode resolution and density are the major factors supporting the growth of brain research. Despite improvements in optical imaging and other modalities, recordings of neural electrophysiology give the … Read More

Finding the Perfect Fit: A Guide to Choosing the Right Research Lab

Alyssa Wright-Brown

Choosing the right research lab to join can be a daunting task for any graduate student or postdoc. Your decision can have a significant impact on your research career and even your personal life. Joining a research lab is a long-term commitment, and it is essential to find a lab … Read More

Spike Sorting Basics: How Do I Know I Have a Good Unit?

Kristin Dartt

We get this question a lot at Plexon, both from brand-new labs and labs that have been recording for years. However, when spike sorting, a “good” unit is very subjective and depends on several things: the recording region, what electrodes are used, how secure the animal ground is (see ground … Read More

Don’t be a Hoarder: Only Save What you Need

Andrew Klein

A common question we receive at Plexon is about processing large data files in Offline Sorter. The details of these discussions are important. “Large” can mean a file a few GB in size or hundreds of GB in size (no joke). “Processing” can mean anything from opening and exporting a … Read More

9 Ways to Improve Your Mental Health

Alyssa Wright-Brown

Social distancing, self-isolation, and lockdowns during the COVID-19 pandemic have resulted in fewer face-to-face interactions with others, and there is evidence that this has negatively affected mental health.1 On top of dealing with the “new normal”, post-docs have the added stress of job security, working long hours and receiving low pay … Read More

Upset About Teaching in Graduate School

Nioka Burns

Forced to Teach while in Graduate school? Take advantage of the System Teaching takes away from research, but here are some ways to get the most out of your assistantship. I was naïve when I started graduate school. No one in my family had gone to college much less graduate … Read More

Open-Source Fiber Photometry Data Analysis Packages: pMAT vs. GuPPY

Kristin Dartt

Overall conclusion: pMAT is more user friendly, but GuPPY has more options and flexibility Summary Comparison Table   One of the major hurdles for a lab performing fiber photometry is data analysis. Using and applying an isosbestic control requires a complex set of mathematics and understanding how to do this … Read More

Can I Start a Family and Still Get Tenure?

Penny Kalvin

Being a researcher demands a lot from a person. One neuroscientist revealed in a Nature article how she works countless hours a day. As a result, her work and mental health suffered from burnout. Over time, however, she eventually learned how to work around her schedule, so that she always has time … Read More

Grounding and Referencing for Electrophysiology Recording Systems

Andrew Klein

It has been said, an informed consumer is the best customer. At Plexon Inc, our goal is for users to be as informed as possible, such that they can ask and answer interesting and unique research questions with equipment purchased by Plexon Inc. To meet that goal, we periodically generate … Read More