Publication Alert
June 13 2023
Development of a synchronous recording and photo-stimulating electrode in multiple brain neurons
In this study, the researchers aimed to develop a compact and ultra-light opto-electrode capable of simultaneously recording and stimulating multiple brain regions. To achieve this, they employed cutting-edge technologies, including micro-nanofabrication quartz glass modules, laser-cutting electrode microwires, a customized laser-perforated steel sheet array, and a customized printed circuit board (PCB).
Several Plexon products in this study include:
- Plexon 32-Channel Electrophysiology System: The researchers utilized Plexon's advanced 32-channel electrophysiology system to conduct high-quality electrophysiological recordings. This state-of-the-art system provides a reliable platform for capturing neural activity with exceptional accuracy and precision.
- CinePlex for Video Synchronization: To synchronize video data with electrophysiological recordings, the researchers relied on CinePlex. This seamless integration of video data enhances the comprehensive analysis of neural activity and behavioral responses.
- Plexon Offline Sorter for Spike Sorting: The researchers employed Plexon Offline Sorter to conduct spike sorting. This sophisticated software facilitates the extraction of meaningful information from recorded neural data, allowing for in-depth analysis and interpretation.
The researchers successfully placed the novel opto-electrode and achieved high-quality electrophysiological recordings from the default mode network (DMN) of the mouse brain. This breakthrough technology enables synchronous recording and stimulation in multiple brain regions.
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