SiNAPS
Simultaneous Neural Recording Active Pixel Sensor Technology
Plexon Inc and Corticale have partnered to offer SiNAPS , an implantable active pixel sensor CMOS-probe for simultaneous large-scale neural recordings. These small-area, ultra low-power active implantable devices enable high-resolution brain activity recordings with the highest electrode array density and minimal wiring available on the market.
SiNAPS
Simultaneous Neural Recording Active Pixel Sensor Technology
Plexon Inc and Corticale have partnered to offer SiNAPS , an implantable active pixel sensor CMOS-probe for simultaneous large-scale neural recordings. These small-area, ultra low-power active implantable devices enable high-resolution brain activity recordings with the highest electrode array density and minimal wiring available on the market.
SiNAPS probes are high-channel count, active electrodes, similar to other active silicon probes available and popular today (E.g., Neuropixels). However, what makes SiNAPS probes unique is the ability to record from all the electrode sites, not only a subset. This means a user can record from all 256 pixels of a 256 pixels SiNAPS probe. The same is true for the 512 pixels and 1,024 pixels probes.
SiNAPS probes require an OmniPlex data acquisition system from Plexon. Please contact your salesperson at Plexon for more information or reach out via info@plexon.com.
SiNAPS in Comparison to Neuropixels?
-
Acquisition From All Pixels: Not a subset like other active silicon probes
-
Fully Supported Software, Hardware and Peripherals
-
Integrated Video Tracking Available (i.e. CinePlex)
- Single Shank and Multi-Shank Configurations
Available Configurations
| Amplifier | In-pixel (DC-input) | |
| Electrode Size | 15 x 15 µm² | |
| Electrode Pitch | 29 μm | |
| Sampling Frequency | 40 kHz/channel effective sampling rate | |
| Electrode/Channels | 256, 512, 1024 | |
| Shank Separation | 560 µm (only for multi-shank probe) | |
| RMS noise | 6.5 µV (in action potential band) | |
| Electrode Material | Pt | |
| Power Consumption | <6 µW/electrode-pixel |
Dimensions: Click the appropriate option below to learn more about the dimensions for each type.
Videos
Technical Specs and Data Sheets
- Khanzada, Shahrukh, et al. Experience Reorganizes Coordinated Population Dynamics across Hippocampal Circuits
2023
- Perna, A. et al. Advancing the interfacing performances of chronically implantable neural probes in the era of CMOS neuroelectronics
2022
- Ribeiro, J. F. et al. Channels, layout and size scalability of implantable CMOS-based multielectrode array probes
2021
- Boi, F. et al. Coupling sinaps high-density neural recording CMOS-probes with optogenetic light stimulation.
- Ribeiro, J. F. et al. Bioelectrodes for high-channel count and small form factor CMOS neural probes
2020
- Boi, F. et al. Multi-shanks SiNAPS Active Pixel Sensor CMOS probe: 1024 simultaneously recording channels for high-density intracortical brain mapping
2019
- Angotzi, GN. et al. SiNAPS: An implantable active pixel sensor CMOS-probe for simultaneous large-scale neural recordings
SiNAPS probes are high-channel count, active electrodes, similar to other active silicon probes available and popular today (E.g., Neuropixels). However, what makes SiNAPS probes unique is the ability to record from all the electrode sites, not only a subset. This means a user can record from all 256 pixels of a 256 pixels SiNAPS probe. The same is true for the 512 pixels and 1,024 pixels probes.
SiNAPS probes require an OmniPlex data acquisition system from Plexon. Please contact your salesperson at Plexon for more information or reach out via info@plexon.com.
SiNAPS in Comparison to Neuropixels?
-
Acquisition From All Pixels: Not a subset like other active silicon probes
-
Fully Supported Software, Hardware and Peripherals
-
Integrated Video Tracking Available (i.e. CinePlex)
- Single Shank and Multi-Shank Configurations
Available Configurations
| Amplifier | In-pixel (DC-input) | |
| Electrode Size | 15 x 15 µm² | |
| Electrode Pitch | 29 μm | |
| Sampling Frequency | 40 kHz/channel effective sampling rate | |
| Electrode/Channels | 256, 512, 1024 | |
| Shank Separation | 560 µm (only for multi-shank probe) | |
| RMS noise | 6.5 µV (in action potential band) | |
| Electrode Material | Pt | |
| Power Consumption | <6 µW/electrode-pixel |
Dimensions: Click the appropriate option below to learn more about the dimensions for each type.
Videos
Technical Specs and Data Sheets
- Khanzada, Shahrukh, et al. Experience Reorganizes Coordinated Population Dynamics across Hippocampal Circuits
2023
- Perna, A. et al. Advancing the interfacing performances of chronically implantable neural probes in the era of CMOS neuroelectronics
2022
- Ribeiro, J. F. et al. Channels, layout and size scalability of implantable CMOS-based multielectrode array probes
2021
- Boi, F. et al. Coupling sinaps high-density neural recording CMOS-probes with optogenetic light stimulation.
- Ribeiro, J. F. et al. Bioelectrodes for high-channel count and small form factor CMOS neural probes
2020
- Boi, F. et al. Multi-shanks SiNAPS Active Pixel Sensor CMOS probe: 1024 simultaneously recording channels for high-density intracortical brain mapping
2019
- Angotzi, GN. et al. SiNAPS: An implantable active pixel sensor CMOS-probe for simultaneous large-scale neural recordings
SiNAPS probes are high-channel count, active electrodes, similar to other active silicon probes available and popular today (E.g., Neuropixels). However, what makes SiNAPS probes unique is the ability to record from all the electrode sites, not only a subset. This means a user can record from all 256 pixels of a 256 pixels SiNAPS probe. The same is true for the 512 pixels and 1,024 pixels probes.
SiNAPS probes require an OmniPlex data acquisition system from Plexon. Please contact your salesperson at Plexon for more information or reach out via info@plexon.com.
SiNAPS in Comparison to Neuropixels?
-
Acquisition From All Pixels: Not a subset like other active silicon probes
-
Fully Supported Software, Hardware and Peripherals
-
Integrated Video Tracking Available (i.e. CinePlex)
- Single Shank and Multi-Shank Configurations
Available Configurations
| Amplifier | In-pixel (DC-input) | |
| Electrode Size | 15 x 15 µm² | |
| Electrode Pitch | 29 μm | |
| Sampling Frequency | 40 kHz/channel effective sampling rate | |
| Electrode/Channels | 256, 512, 1024 | |
| Shank Separation | 560 µm (only for multi-shank probe) | |
| RMS noise | 6.5 µV (in action potential band) | |
| Electrode Material | Pt | |
| Power Consumption | <6 µW/electrode-pixel |
Dimensions: Click the appropriate option below to learn more about the dimensions for each type.
Videos
Technical Specs and Data Sheets
2023
- Perna, A. et al. Advancing the interfacing performances of chronically implantable neural probes in the era of CMOS neuroelectronics
2022
- Ribeiro, J. F. et al. Channels, layout and size scalability of implantable CMOS-based multielectrode array probes
2021
- Boi, F. et al. Coupling sinaps high-density neural recording CMOS-probes with optogenetic light stimulation.
- Ribeiro, J. F. et al. Bioelectrodes for high-channel count and small form factor CMOS neural probes
2020
- Boi, F. et al. Multi-shanks SiNAPS Active Pixel Sensor CMOS probe: 1024 simultaneously recording channels for high-density intracortical brain mapping
2019
SiNAPS probes are high-channel count, active electrodes, similar to other silicon active probes available and popular today (E.g., Neuropixels). However, what makes SiNAPS probes unique is the ability to record from all the electrode sites, not only a subset. This means a user can record from all 256 channels of a 256 channel SiNAPS probe. The same is true for the 512 channel and 1,024 channel probes.
SiNAPS probes require an OmniPlex data acquisition system from Plexon. Please contact your salesperson at Plexon for more information or reach out via info@plexon.com.
SiNAPS in Comparison to Neuropixels?
-
Acquisition From All Pixels: Not a subset like other active silicon probes
-
Fully Supported Software, Hardware and Peripherals
-
Integrated Video Tracking Available (i.e. CinePlex)
- Single Shank and Multi-Shank Configurations
Available Configurations
| Amplifier | In-pixel (DC-input) | |
| Electrode Size | 15 x 15 µm² | |
| Electrode Pitch | 29 μm | |
| Sampling Frequency | 40 kHz/channel effective sampling rate | |
| Electrode/Channels | 256, 512, 1024 | |
| Shank Separation | 560 µm (only for multi-shank probe) | |
| RMS noise | 6.5 µV (in action potential band) | |
| Electrode Material | Pt | |
| Power Consumption | <6 µW/electrode-pixel |
Dimensions: Click the appropriate option above to learn more about the dimensions for each type.
Videos
Technical Specs and Data Sheets
- Khanzada, Shahrukh, et al. Experience Reorganizes Coordinated Population Dynamics across Hippocampal Circuits
2023
- Perna, A. et al. Advancing the interfacing performances of chronically implantable neural probes in the era of CMOS neuroelectronics
2022
- Ribeiro, J. F. et al. Channels, layout and size scalability of implantable CMOS-based multielectrode array probes
2021
- Boi, F. et al. Coupling sinaps high-density neural recording CMOS-probes with optogenetic light stimulation.
- Ribeiro, J. F. et al. Bioelectrodes for high-channel count and small form factor CMOS neural probes
2020
- Boi, F. et al. Multi-shanks SiNAPS Active Pixel Sensor CMOS probe: 1024 simultaneously recording channels for high-density intracortical brain mapping
2019