OmniPlex 1.11 Released and Plexon News
Plexon’s newsletter from January 29, 2014 discusses the release of a new OmniPlex system as well as Plexon’s record growth.
|January 29, 2014|
What a year! Welcome to the 120+ new laboratories from 18 countries that relied on Plexon’s equipment for the first time in 2013. We are delighted to be such a trusted partner to so many performing amazing and critical research around the globe. Welcome to the Plexon family, and thank you for the confidence you placed in us.
We eagerly await the next opportunity to serve and support these new customers, just as we do our valued, existing customers in the weeks, months and years to come. Just give us a call and let us know what we can do for you!
Early Registration for Workshop ends February 28
Workshop dates: March 17-20, 2014
Registration fees have remained flat for the third year in a row, AND this year there is an added discount if a registration is included on a quote for an OmniPlex®, CinePlex® or MAP System that is ordered by February 28, 2014. Registration pricing is as follows:
The Workshop is limited to no more than 40 attendees to ensure maximum hands-on experience. Letters for Visa applications are available. For more information, email firstname.lastname@example.org.
OmniPlex 1.11 Released
OmniPlex users – stop what you are doing and download OmniPlex 1.11! This release is packed full of new features and performance enhancements including the significant addition of the new Spectral view, timed recording options, robust statistics, t-distribution expectation maximization (TDEM) auto-sorting algorithm and faster processing among other improvements. Importantly, OmniPlex 1.11 now sets the default recording format to PL2.
A simple yet significant change in this new release is that the recording file format now defaults to Plexon’s game-changing PL2™ launched last year. The legacy PLX format is still supported; however, it is no longer the default. PL2 is supported by the latest versions of Offline Sorter™ (OFS), NeuroExplorer®, and Plexon’s MATLAB® and C/C++ file reading software development kits (SDKs) available online. It is important to make sure that the applications, scripts and other programs which are intended to be used to view and analyze recorded OmniPlex data support are updated to the new PL2-compatible format. If in doubt, contact email@example.com.
OmniPlex 1.11 now also offers a sophisticated, visually rich, new view: the Spectral view. It displays a rolling color-coded spectrogram of the currently selected field potential (FP) channel, plus an animated spectral graph below it. This allows researchers to monitor changes in spectral content, such as increase in energy in a range of frequencies, as a function of time.
The PlexControl program within the OmniPlex Software now provides options for using robust statistics in the determination auto-thresholding and sorting parameters. The primary advantage of robust statistics is that they are more resistant to the effect of outliers. Researchers will typically find that using robust statistics produces a more accurate estimate of the noise distribution, with the presence of spikes having less influence on the auto-thresholding process.
Previous releases of OmniPlex supported a single auto-sorting algorithm, known as valley seeking. Valley seeking is a non-parametric method based on local density measures, and gives very good results in many cases, but it is not always ideal. OmniPlex 1.11 supports an additional auto-sorting algorithm called t-distribution expectation maximization (TDEM). TDEM works on the assumption that the clusters in feature space (each cluster representing the spikes from one neuron) can be modeled as t-distributions, so that the entire set of clusters on each channel is a mixture of t-distributions. The TDEM algorithm solves a global optimization problem to find the set of t-distributions which best fit the observed clusters on each spike channel.
From a purely practical perspective, researchers will likely appreciate that timed recording options are now supported. Timing of the Start, Stop, Pause and Resume commands can be specified.
In addition to the expanded functionality listed above, several existing functions operate significantly faster in release 1.11. These include auto-thresholding, the initial calculation of the PCA projections (and manual PCA recalculation using the PCA button), and Delete All Units on All Channels. These performance improvements will be especially noticeable at high channel counts.
This latest download can be found on the OmniPlex System webpage, and at plexon.com/software-downloads. For more information regarding these or other improvements, please read the Release Notes contained within the install package.
NEW Radiant™ 2.0 for Optogenetic Stimulation
Radiant™ and the PlexBright™ 4 Channel Controller are the cornerstones of the PlexBright Optogenetic Stimulation System (PlexBright System). Together, they offer unsurpassed control of LEDs and/or lasers over multiple, independent channels. Radiant 2.0’s newly enhanced pattern generation functionality allows researchers to quickly define simple to complex output patterns that may be saved and played back repeatedly. Pattern definition can even be performed offline for later use! Further, arbitrary stimulation patterns can be loaded from user defined text files, or the outputs can be controlled directly by the user in manual mode.
Signals may be configured to enable simultaneous control of both LED modules and lasers. With an additional eight digital inputs and 16 digital outputs, Radiant 2.0 and the PlexBright 4 Channel Controller can easily interface with third-party equipment as part of a more elaborate experimental set-up. For higher volume research experiments, Radiant 2.0 enables the integration of up to four PlexBright 4 Channel Controllers simultaneously operated by a single computer – yielding up to 16 channels of independent output.
It is important to note, Radiant 2.0 now requires a license key to operate. If you currently have any previous version of Radiant operating on your computer, do not download Radiant 2.0 without already having the license key to operate the software. Contact firstname.lastname@example.org with any questions.
Click for more information about Radiant 2.0 and the PlexBright 4 Channel Controller or email email@example.com.
FREE Radiant 2.0 and 4 Channel Controller Upgrades
As a demonstration of Plexon’s appreciation and good will during the holidays, Plexon offered a complimentary upgrade to Radiant 2.0 AND the most advanced version of the PlexBright 4 Channel Controller hardware for all customers who placed an order for a PlexBright 4 Channel Controller with Radiant in 2013.
Purchasers should have been contacted by now, but if not, please reach out to firstname.lastname@example.org with any questions about the complimentary upgrade. We trust you will enjoy the remarkably robust control over your optogenetic stimulation experiments that the newest combination of software and hardware will provide.
NEW PlexBright Optogenetic Stimulation Starter Kits
Introducing PlexBright Optogenetic Stimulation System Starter Kits specific to your experimental set-up – PLUS a 10% discount. Starter Kits have been developed for the following scenarios:
There are two Starter Kits for each type of experimental set-up: an Economical starter kit and a Fully Functional starter kit. They both contain the same components with the exception of the optogenetic driver. The Economical Starter Kit includes the PlexBright LD-1 Single Channel LED Driver, while the Fully Functional Starter Kit contains the PlexBright 4 Channel Controller with Radiant software for advanced functionality across multiple independent channels driving LEDs and/or Lasers simultaneously.
For more information on the Starter Kit contents, see the newly posted PlexBright Quote Request Forms for each of the experiment set-ups listed above. Forms can be found on the Resources tab of any PlexBright product webpage, or on the Documentation page under PlexBright.
Let us know about your 2013 publication citing Plexon and our equipment and we will send you a thank you award with a mug and a T-shirt! Send notices, address and T-shirt size to email@example.com.
All articles listed are alphabetical based on first author within two categories: articles published online in electronic-only journals or ahead of print, and articles published in full print.
Recent articles published online in electronic-only journals or ahead of print:
Recent articles published in full print:
Documentation – You asked for it!
In response to requests for more documentation, the Plexon team generated and posted more than 30 new technical documents online in 2013! You asked and we listened . . . and we are not done yet! Watch the website for many more to come.
Get Ready . . . . PlexBright™/JoVE Contest Coming Soon
Calling all labs with PlexBright equipment! We will be running a second Publication Grant Contest in partnership with the Journal of Visualized Experiments (JoVE) – this time for research conducted using the PlexBright™ Optogenetic Stimulation System – a $4,200 value! Watch for more information and begin collecting your data!!
NEW PlexBright Quote Request Forms
To better manage the tidal wave of interest in quotes for the PlexBright Optogenetic Stimulation System products, we have launched NEW PlexBright Quote Request Forms specific to your research scenario:
• Freely Behaving Rat and Larger Animals
They can be completed electronically and sent to either firstname.lastname@example.org or faxed to +1 (214) 369-1775. A quote will be sent to you shortly thereafter. Forms are located on the Resources tab for any PlexBright product webpage, or on the Documentation page under PlexBright.
• Computational and Systems Neuroscience (Cosyne) 2014, February 27 – March 2; Salt Lake City, UT, USA