High-density μLED Optoelectrodes for Local Circuit Mapping”

In this webinar, we will review the evolution of Michigan neural probe technologies toward scaling up the number of recording sites and enabling precise neuromodulation by optogenetic stimulation. Modular system integration and compact 3D packaging approaches have been explored to realize high-density neural probe arrays for recording of more than 1,000 channels simultaneously. In order to obtain optical neuromodulation, we monolithically integrated micro-LEDs on the probe shank to achieve high spatial temporal modulation of neural circuits. We have demonstrated independent control of distinct cells ~50 μm apart and of differential somato-dendritic compartments of single neurons in the CA1 pyramidal layer of anesthetized and freely-moving mice.

Euisik Yoon, Professor, University of Michigan

Euisik Yoon received the Ph.D. degree in electrical engineering from the University of Michigan, Ann Arbor, in 1990.

He worked for industries for six years including the Fairchild Research Center of the National Semiconductor Corp. in Santa Clara, CA and for Silicon Graphics Inc. in Mountain View, CA, before he returned to academia. He took faculty positions at Korea Advanced Institute of Science and Technology (KAIST) in Daejon, Korea and the University of Minnesota, Minneapolis, MN, respectively. In 2008, he joined the Department of Electrical Engineering and Computer Science at the University of Michigan, Ann Arbor, MI, where he is a Professor. He served as the Director of Lurie Nanofabrication Facility at the University of Michigan from 2011 to 2016. Currently he is the lead-PI of the NSF NeuroNex Michigan Hub (MINT) to disseminate neurotechnologies to the science community.